Estée Lauder patents a new approach to lipofuscin treatment



Estée Lauder Companies has filed a new patent that addresses one of the most challenging aspects of skin aging—lipofuscin, or “age pigment.” This patent introduces a novel composition designed to target lipofuscin accumulation in the skin, which is strongly associated with the appearance of age spots and other pigment-related imperfections.

The formulation holds intriguing implications for manufacturers and suppliers in the cosmetics and personal care industry, as it provides a pathway for developing innovative anti-aging skincare products.

Lipofuscin and its role in aging

Lipofuscin is a complex yellow-brown pigment that accumulates in human tissues with age and is recognized as one of the key contributors to the formation of age spots. The patent describes lipofuscin as “a complex mixture of protein and lipid derivatives, showing yellow-brown color under optical microscopes and having autofluorescence properties.”

Due to its strong correlation with aging, reducing lipofuscin has long been a priority in the cosmetics industry.

However, traditional approaches to treating lipofuscin have been largely ineffective because “lipofuscin is known as a difficult pigment to remove once produced in the skin.” Furthermore, there is still limited scientific understanding of the exact mechanisms responsible for its generation, making it difficult to develop targeted treatments.

The innovation: Decarboxylated oligopeptide and pyracantha extract

The new patent outlines a product composition that combines decarboxylated oligopeptides, particularly Decarboxy carnosine HCL, with Pyracantha fortuneana​ fruit extract. According to the filing, this combination has shown “unexpected synergistic effects on preventing or slowing lipofuscin generation and/or accumulation.” This means that together, these ingredients are more effective at reducing lipofuscin than when used independently, which marks a noteworthy innovation in pigment treatment strategies.



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